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An interesting open source project: EPICS is the "Experimental Physics and Industrial Control System"

What is EPICS?

EPICS is a set of software tools and applications which provide a software infrastructure for use in building distributed control systems to operate devices such as Particle Accelerators, Large Experiments and major Telescopes. Such distributed control systems typically comprise tens or even hundreds of computers, networked together to allow communication between them and to provide control and feedback of the various parts of the device from a central control room, or even remotely over the internet.

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NASA GRC is interested / working with this.