;IPv6 : Internet Protocal version 6
;IPR : Intellectual Property Rights
;IRL : In Real Life = A TLA used when 'virtual' was a thing. Now the virtual has permeated 'meat space' and so the two are not so distinct.
;ISBN : International Standard Book Number. ISBNs are 10-digit or 13-digit codes used by the publishing industry to uniquely identify individual book titles and editions. Some 10-digit ISBNs may end with an "X" instead of a digit.
;JS : JavaScript. A computer language.