<li>If you plan to use the CiviCase component to manage the common constituent "projects" or "workflows" and their associated timelines, then you'll need to create your own "Case Types". Look at the existing "Case Types" for reference.
<li>{{@todo}} review [http://wiki.civicrm.org/confluence/display/CRMDOC/Managing+Scheduled+Jobs docs] and setup cron to do things like geocoding
<li>Test and set your SPF record for your domain so that you can use Mailer, and review the docs for [http://book.civicrm.org/user/current/advanced-configuration/email-system-configuration/ email system configuration]
</ol>